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Mass spectrometry is a scientific technique for measuring the mass-to-charge ratio of ions. It is often coupled to chromatographic techniques such as gas- or liquid chromatography and has found widespread adoption in the fields of analytical chemistry and biochemistry where it can be used to identify and characterize small molecules and proteins (proteomics). The large volume of data produced in a typical mass spectrometry experiment requires that computers be used for data storage and processing. Over the years, different manufacturers of mass spectrometers have developed various proprietary data formats for handling such data which makes it difficult for academic scientists to directly manipulate their data. To address this limitation, several open, XML-based data formats have recently been developed by the Trans-Proteomic Pipeline at the Institute for Systems Biology to facilitate data manipulation and innovation in the public sector. These data formats are described here.

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  1. G

    UFH seems to have a problem

    I have two adjoining cottages, each with an identical UFH system downstairs. Both been going fine for around five years. But for the last few weeks, one of the systems doesn't seem to be running most of the time. Essentially the UFH does "work", in that I can turn the thermostat right up, and...
  2. C

    Radiator never seems to turn off

    I am completely clueless about heating, so I hope one of you knowledgeable souls can help. My mother is bedbound with dementia, and I am trying to understand her heating system. The house and heating system is about 40 years old, I think, but the gas boiler was changed maybe 10 years ago. It is...
  3. M

    My t valve seems to be too thick for my shark bite cylinder

    I cannot get my shark bite fitting to fit over the white supposed to be a half inch copper T valve is it because it’s corroded just seem to be too thk
  4. T

    Thermo Evocyl seems to be on 24/7 and noisy

    Cylinder pump makes a noise 24/7 and is next to the bedroom. This is a brand new house and the noise actually keeps us awake at night. Plumber came and said that's just the way it is. Surely in this day and age a system isn't designed to make a noise permanently. Any advice on what to do next...
  5. D

    My hot water seems far too hot 🥵

    Greetings members of plumbersforums, Firstly - long post alert I’m struggling with my hot water currently - I’ve only mainly dealt with combi boilers, even then, not really had hot water too hot. Anyway I digress, my system is an open vented pre-lagged cylinder, S-plan, Myson 2 ports with a...
    • Deleted member 120897
    • Thread
    • america far hot hot water seems usa water
    • Replies: 62
    • Forum: USA
  6. M

    Harvey Water softener seems to have stopped regenerating

    Our HV3 is about 7.5 years old and has just stopped regenerating. Do any of you good people have any ideas of anything I could try before calling Harveys? thx
  7. A

    Gas safety report seems strange

    Hi I'm currently in the process of buying a house and received a gas safety certificate for the property dating back to May. On the report it stated some defects with the boiler upon querying this with my solicitor we where send a new gas safety certificate from the vendor that states there is...
  8. D

    Motorised valve seems way too hot

    Bit of a puzzle with home heating - 18yr old 'Y' Plan system with 12 rads, one big and one small cold header tanks in loft and a hot cylinder with coil in first floor airing cupboard. Two weeks ago heating stopped working - but hot water production still OK. For a few days following, if I moved...
    • Doh!
    • Thread
    • america hot motorised motorised valve seems usa valve
    • Replies: 14
    • Forum: USA
  9. davidw

    Thermostat and valves configuration seems odd

    We’ve just moving to a new house. I’m puzzled with the central heating system and its controls. None of the downstairs radiators have thermostatic valves fitted, all of the upstairs rads do. There is a thermostat in the hall which it seems controls all the heating ? So the only way of...
  10. U

    Hi all. CH fails to work on timed / auto. Constantly seems to cavitate.

    Ideal Icos HE18. Y plan. Ok when on constant. Set to auto and when firing up of an evening, banging and clattering. Any suggestions pls?
    • Ukstealthbomber
    • Thread
    • auto constantly he18 icos ideal seems timed urgent winter work
    • Replies: 3
    • Forum: Canada
  11. C

    Saniflo water pressure seems low

    Hi, Last night our Saniplus unit started running continuously, failing to pump out water. I tried looking for blockages but couldn't find any. When I disconnected the discharge pipe and directed it into a bucket, water was pumped out ok but the pressure seemed fairly low. Having spent quite a...
  12. B

    Radiators cold when heating is on - Offsite Heating, Pressure seems fine.

    Hi, I tried to turn my heating on but my radiators are staying cold, I added more water to the system which raised the pressure but there was no change, i've made sure the radiators are bled and nothing has changed since last year when all of this was working. I've attached some pictures of my...
  13. N

    Central heating header tank seems to be overflowing...

    Can anyone advise... I believe it is the central heating (for radiators) header tank that is overflowing from time to time - ie once or twice a day for a few minutes (it appeared to start again today shortly after the central heating came on - and then the pouring/dripping stopped after a few...
  14. P

    Combi CH seems to be randomly working, HW is fine, Help!

    Hi, Viessmann Vitodens 100-W, with Vitotrol 100 wireless digital thermostat. I'm not a plumber and just trying to help an old friend out if I can. I've bled air out of the boiler a couple of times, as it was very noisy, this seems to of quietened it down. Some radiators don't get warm, but a...
  15. D

    Cold water seems fine , no hot.

    Afternoon all, looking for some advice please, Hot water was fine this morning now barely dribbles out, cold is fine. I have complete New system from 2009 (Rebuild ) Heatrae megaflow and main system 28 HE boiler, pressure on boiler is 1.5 bar, boiler firing, heating working, no apparent water...
  16. V

    Main Combi HE needing high flow rate to trigger DHW

    Hi everyone - not been on here in ages, but know someone will have some sound advice :-) My Mother has just had her Main Combi 30 HE serviced by her regular guy - Expansion vessel needed recharging and all seem well but after he left I found there was no hot water unless the taps were turned...
  17. Jock Spanners

    Linking oil fired central heating to a wood burning stove

    Hi Everyone, I've been asked to install a new oil fired central heating system and link it to a wood burning stove. It's in a bungalow refurb and the customer has an unlimited supply of wood. I'm very skeptical of it all working. It seems to me the choice is between a thermal store, H2 panel...
  18. N

    Ideal Logic Combi 35 - leaking around siphon trap

    Hi, I noticed some dripping from my boiler today and upon investigation I can see that it has been leaking around the siphon trap holes at the bottom of the boiler. I took the front off and the siphon which was quite dirty with some greyish grit in the 'sump like plug' at the bottom. After a...
    • neildon
    • Thread
    • around bottom combi ideal ideal logic leaking logic quite seems siphon trap
    • Replies: 6
    • Forum: Plumbing Jobs | The Job-board
  19. T

    What's this shower valve? No branding!

    Hello all. Quick question. Does anyone know what brand of shower valve this is (for some reason, the picture seems to turn on its side when I insert it - should show with all valve handles vertical)? There is no branding marked on it anywhere, but it seems high quality stuff. I have spent...
  20. M

    Rads cooler at the bottom

    Have a Worcester 30i with new rads bar 2, magna clean and descale fitter but bar 2 rads all others are hot at top but much cooler at the bottom. Any ideas what it could be? Google seems to suggest sludge or balancing rads and am erring towards latter as sludge would not be issue in the...
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